When MDD reduces the amount of gray matter, this disturbs the passage of these neurotransmitters, leading to the disorder’s symptoms.įactors that increase the chances of developing MDD include: The neurotransmitters serotonin, dopamine, and norepinephrine travel through gray matter. Gray matter is involved in numerous processes, including speech, decision-making, and self-control. MDD also reduces the amount of gray matter in the brain. A reduction in the size of this part of the brain can affect its ability to function. The hippocampus helps make memories, adapt to stressful situations, and process emotions. In a person with MDD, the hippocampus is smaller than it is in a person without the disorder. However, researchers believe the part of the brain called the hippocampus plays a large part in MDD. In the case of MDD, scientists do not yet know how these factors interact, and they believe that each symptom of MDD may have different causes. Mood disorders have genetic and external causes.

While some causes of MDD and PDD may be similar, there are some crucial differences. They may withdraw from friends and activities they once enjoyed.

The person may find it hard to work, attend school, or take care of home and family responsibilities. Social functioning can also become difficult with MDD. Many people with MDD also have substance abuse disorders. Those with MDD may also experience symptoms of panic disorders, social anxiety disorder, and obsessive-compulsive disorder, as well as other mental health disorders. experiencing a type of restlessness called psychomotor agitation or finding it difficult to think, speak, and do other everyday things, called psychomotor impairment.having trouble sleeping - insomnia - or sleeping too much.unintentionally losing or gaining a significant amount of weight.having difficulty concentrating and making decisions.having less interest or pleasure in most or all activities.having a depressed mood that lasts for most of the day.MDD symptomsĪs with PDD, not every symptom has to be present at the same time for a doctor to diagnose the issue. It may also cause an increase in overwhelming feelings during stressful situations. The condition can also make socializing and enjoying hobbies difficult. Those with PDD may experience difficulties in fulfilling work, school, or home responsibilities. In these cases, the symptom only needs to be present for 1 year. having trouble concentrating or making decisionsĬhildren and adolescents with PDD may experience irritability as a symptom instead of depression.Not every PDD symptom needs to be present at the same time for a person to receive a diagnosis. The symptoms of PDD somewhat overlap with those of MDD. A person can have symptoms of both disorders at the same time.

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